Niclosamide And Its Multiple Uses

Posted January 7, 2022 by in Health + Fitness

Information shows the pharmacologic actions of Niclosamide are able to make it usable for lots of things. Those effects result from the medicine’s ability to separate mitochondrial phosphorylation as well as regulate a range of signaling pathways.

Repurposing studies have revealed diverse possibilities for treating diabetes, as well as Parkinson’s, and for viral and microbial illnesses, to include some kinds of cancer. 


A little more than one in ten people in America have developed diabetes. This translates into nearly 35 million folks. One in three, or about eighty-eight million people in America also have prediabetes, which is quite a serious problem. Since this metabolic issue seems so prevalent, it is logical to search for other kinds of treatments which could offer lots of helpful results. 

The salt format of Niclosamide (Niclosamide ethanolamine works better in regards to water solubility, and it additionally got rid of type 2 diabetes symptoms in experiments with rodents. The mice were fed  a diet high in fat and presented a high use of energy, as well as  better lipid oxidation, and help with the metabolism. Niclosamide ethanolamine proved efficient for management of hyperglycemia (high blood sugar), as well a controlling glycemic issues, and decreasing the progress of the disease. 

Parkinson’s Disease (PD)

Any metamorphoses of the catalytic action of the mitochondrial serine/threonine-protein kinase PINK1 could cause PD to come into a person’s body earlier than normal. Small molecules which trigger that issue would provide neuroprotective effects. Therefore, they carry the possibility of treating this illness. 

Niclosamide capsules is a potent activator for PINK1 in cells, that means it provides considerable promise of keeping this illness in check. However, additional PD models are needed to prove the drug’s ability to treat this illness. 

Viral Infections

Folks are able to be infected by viruses via swallowing or inhaling them. They additionally might get it via sexual intercourse or being bitten by an insect. Viral infections affect a person’s upper airways, along with the nose and throat, as well as bodily systems like the nervous, reproductive and gastrointestinal systems. Many times antiviral drugs are employed for curbing reproduction of a virus and to keep a person’s immune system in good shape. 

Niclosamide likewise could possibly be utilized as a broad-spectrum antiviral agent. It would be able to target the host’s pathways. That action has been linked with the drug’s possibility of mitigating these infections. As of now, a few studies have tested utilizing Niclosamide to treat COVID 19, as well as the Zika and Ebola viruses. 

Bacterial Infections

Bacteria infects a person’s body whenever it gets into your system. So it then reproduces itself and triggers certain reactions. You might also get it due to it getting inside an open wound or via your airway. Niclosamide was revealed to have a antimicrobial potential to fight some kinds of bacterial infections. This would mainly include tuberculosis, anthrax, as well as methicillin-resistant Staphylococcus aureus  or MRSA. These discoveries indicated this medicine works as good as vancomycin, which is the drug used now to treat MRSA.   


Professionals have concentrated their resources and attention and resources for many years to find ways to fight cancer. Niclosamide presented several anticancer actions to fight against these types of cancer:

  • Breast
  • Colon 
  • Lung
  • Prostate
  • Ovarian
  • Leukemia
  • Glioblastoma
  • Osteosarcoma
  • Adrenocortical carcinoma
  • Oral cancers

Information shows the medicine’s capability to harm tumor cell mitochondria, as well as impede tumor cell production, and stimulate apoptosis, so it is indeed a feasible option. 

Niclosamide has a major possibility of being used to treat several diseases. Obviously, like any other drug now in use, it does have a few safety fears. Additional research is needed to dig deeper into any safety issues and find out its full potential. The data now available merely highlights the drug’s effect as well as its versatility. This proves this drug may provide many kinds of medicinal activities. 

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*Talk to your doctor before starting any new medication.

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